lizanalab's website

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The life sciences have witnessed an unprecedented surge in data, encompassing genomics, transcriptomics, proteomics, and imaging technologies. While statistical and machine-learning approaches have provided valuable insights, they often lack the ability to unveil cause-and-effect relationships. Therefore, our group takes a different approach. We specialize in developing mechanistic models that integrate diverse datasets that offers deeper insights into biological processes and more reliabile predictions.

In collaboration with experimentalists, we tackle a wide array of topics, including biological networks, gene regulation, epigenetics, aging, intermittent search problems, polymer physics, and DNA folding in the cell nucleus. Additionally, we engage in interdisciplinary collaborations with earth scientists, employing network models to calculate CO2 emissions in the Arctic.

Explore our website to learn more about our ongoing projects, publications, and opportunities for collaboration.

news

selected publications

  1. Fractal and knot-free chromosomes facilitate nucleoplasmic transport
    Yeonghoon Kim ,  Ludvig Lizana ,  and  Jae-Hyung Jeon
    Physical Review Letters, 2022
  2. Mapping the semi-nested community structure of 3D chromosome contact networks
    Dolores Bernenko ,  Sang Hoon Lee ,  Per Stenberg , and 1 more author
    PLOS Computational Biology, 2023
  3. Forecasting histone methylation by Polycomb complexes with minute-scale precision
    Moa J. Lundkvist ,  Ludvig Lizana ,  and  Yuri B. Schwartz
    Science Advances, 2023